BPC-157
5 mg
Pentadecapeptide derived from gastric protective protein, 5 mg per vial.
- CAS
- 137525-51-0
- Sequence
- GEPPPGKPADDAGLV
- Storage
- Refrigerated
Comparison
BPC-157 vs TB-500
The two most-studied compounds in tissue repair research, frequently named together and frequently assumed to do the same thing. They do not: they come from different source proteins and act through different mechanisms, which is exactly why they are so often studied side by side.
What is the difference between BPC-157 and TB-500?
They are complementary rather than interchangeable. BPC-157 is the reference compound where the research question involves gut mucosa or localised connective tissue. TB-500 is the one where cell migration and remodelling are the endpoints. A protocol comparing the two, or the pre-combined blend, is the usual design when the question is whether the mechanisms are additive.
Side by side
| Property | BPC-157 | TB-500 |
|---|---|---|
| Origin | A 15-amino-acid sequence from human gastric protective protein | The active fragment of thymosin beta-4, a widely expressed actin-binding protein |
| Size | Pentadecapeptide, 1419.5 g/mol | Peptide fragment, 4963.4 g/mol |
| Primary mechanism studied | Angiogenic signalling and growth factor receptor expression | Actin sequestration and cell migration |
| Research emphasis | Gut mucosa and connective tissue models | Cell motility and tissue remodelling models |
| Distribution in study | Studied both systemically and locally | Studied predominantly systemically |
| Stability in solution | Comparatively stable; an arginate salt form extends this further | Standard peptide handling; refrigerate once reconstituted |
| Price | $49.00 · 5 mg | $49.00 · 5 mg |
Both compounds
TB-500
5 mg
Synthetic active fragment of thymosin beta-4, 5 mg per vial.
- Storage
- Refrigerated
Questions
Are BPC-157 and TB-500 the same thing?
No. BPC-157 is a 15-amino-acid sequence derived from a gastric protective protein. TB-500 is a fragment of thymosin beta-4, an actin-binding protein. They differ in origin, in size, and in the mechanisms they are studied for.
Can BPC-157 and TB-500 be combined in one vial?
Yes, and a pre-combined blend is stocked for exactly that reason. Both reconstitute in bacteriostatic water and remain in solution together, which is what makes the combined-versus-individual comparison practical to run.
Which is studied more?
BPC-157 has the larger published literature, particularly in gastrointestinal and tendon models. TB-500 and full-length thymosin beta-4 are better represented in cardiac and corneal work.
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All products listed are sold strictly for in-vitro laboratory research and analytical use. They are not drugs, foods, cosmetics or medical devices, and are not intended to diagnose, treat, cure or prevent any disease.